compound 10 [PMID: 18790648]

Ligand id: 8665

Name: compound 10 [PMID: 18790648]

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 10
Hydrogen bond donors 5
Rotatable bonds 20
Topological polar surface area 207.95
Molecular weight 728.24
XLogP 8.25
No. Lipinski's rules broken 2

Molecular properties generated using the CDK

1. Georgiadis D, Yiotakis A. (2008)
Specific targeting of metzincin family members with small-molecule inhibitors: progress toward a multifarious challenge.
Bioorg. Med. Chem.16 (19): 8781-94. [PMID:18790648]