Ligand id: 9184

Name: clofazimine

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 4
Topological polar surface area 27.63
Molecular weight 472.12
XLogP 7.97
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

1. Arbiser JL, Moschella SL. (1995)
Clofazimine: a review of its medical uses and mechanisms of action.
J. Am. Acad. Dermatol., 32 (2 Pt 1): 241-7. [PMID:7829710]
2. Faouzi M, Starkus J, Penner R. (2015)
State-dependent blocking mechanism of Kv 1.3 channels by the antimycobacterial drug clofazimine.
Br. J. Pharmacol., 172 (21): 5161-73. [PMID:26276903]
3. HRSA. 
National Hansen's Disease (Leprosy) Program.
Accessed on 04/07/2016. Modified on 04/07/2016. HRSA- Health Resources and Services Administration,