nalmefene

Ligand id: 1628

Name: nalmefene

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 2
Hydrogen bond donors 2
Rotatable bonds 2
Topological polar surface area 52.93
Molecular weight 339.18
XLogP 1.55
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes (EMA (2013))
IUPAC Name
(1S,5R,13S,17S)-4-(cyclopropylmethyl)-14-methylidene-12-oxa-4-azapentacyclo[9.6.1.0^{1,13}.0^{5,17}.0^{7,18}]octadeca-7,9,11(18)-triene-10,17-diol
International Nonproprietary Names
INN number INN
5189 nalmefene
Synonyms
JF-1 | nalmetrene | ORF-11676 | Revex® (nalmefene hydrochloride) | Selincro®
Database Links
CAS Registry No. 55096-26-9 (source: Scifinder)
ChEMBL Ligand CHEMBL982
GtoPdb PubChem SID 135650681
PubChem CID 5284594
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Wikipedia Nalmefene
Comments
Nalmefene is an opioid receptor antagonist.