prucalopride

Ligand id: 243

Name: prucalopride

IUPHAR Pharmacology Education Project (PEP) logo

View more information in the IUPHAR Pharmacology Education Project: prucalopride

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 7
Topological polar surface area 76.82
Molecular weight 367.17
XLogP 0.85
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes (EMA (2009))
IUPAC Name
4-amino-5-chloro-N-[1-(3-methoxypropyl)piperidin-4-yl]-2,3-dihydro-1-benzofuran-7-carboxamide
International Nonproprietary Names
INN number INN
7702 prucalopride
Synonyms
R-093877 | R-108512 | Resolor®
Database Links
BindingDB Ligand 50122872
CAS Registry No. 179474-81-8 (source: Scifinder)
ChEMBL Ligand CHEMBL117287
PubChem CID 3052762
Search Google for chemical match using the InChIKey ZPMNHBXQOOVQJL-UHFFFAOYSA-N
Search Google for chemicals with the same backbone ZPMNHBXQOOVQJL
Search PubMed clinical trials prucalopride
Search PubMed titles prucalopride
Search PubMed titles/abstracts prucalopride
Search UniChem for chemical match using the InChIKey ZPMNHBXQOOVQJL-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone ZPMNHBXQOOVQJL
Wikipedia Prucalopride
Comments
Prucalopride is a serotonin 5-HT4 receptor agonist.