meclizine

Ligand id: 2757

Name: meclizine

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 2
Hydrogen bond donors 0
Rotatable bonds 5
Topological polar surface area 6.48
Molecular weight 390.19
XLogP 8.25
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes (FDA (1957))
IUPAC Name
1-[(4-chlorophenyl)-phenylmethyl]-4-[(3-methylphenyl)methyl]piperazine
International Nonproprietary Names
INN number INN
204 meclozine
Synonyms
Antivert® | Dramamine® | Sea-Legs®
Database Links
BindingDB Ligand 81467
CAS Registry No. 569-65-3
ChEMBL Ligand CHEMBL1623
DrugBank Ligand DB00737
NURSA Ligand 10.1621/OMDNLEDB3W
PubChem CID 4034
Search Google for chemical match using the InChIKey OCJYIGYOJCODJL-UHFFFAOYSA-N
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Search UniChem for chemical match using the InChIKey OCJYIGYOJCODJL-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone OCJYIGYOJCODJL
Wikipedia Meclizine
Comments
Meclizine is an antiemetic antihistamine drug.