vincristine

Ligand id: 6785

Name: vincristine

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 13
Hydrogen bond donors 3
Rotatable bonds 11
Topological polar surface area 171.17
Molecular weight 824.4
XLogP 3.56
No. Lipinski's rules broken 2

Molecular properties generated using the CDK

Classification
Compound class Natural product or derivative
Approved drug? Yes (FDA (1963))
International Nonproprietary Names
INN number INN
1440 vincristine
Synonyms
22-oxovincaleukoblastine | kyocristine | leurocristine sulfate | NSC-67574 | Oncovin®
Database Links
CAS Registry No. 57-22-7
ChEBI CHEBI:28445
ChEMBL Ligand CHEMBL90555
DrugBank Ligand DB00541
PubChem CID 5978
Search Google for chemical match using the InChIKey OGWKCGZFUXNPDA-XQKSVPLYSA-N
Search Google for chemicals with the same backbone OGWKCGZFUXNPDA
Search PubMed clinical trials vincristine
Search PubMed titles vincristine
Search PubMed titles/abstracts vincristine
Search UniChem for chemical match using the InChIKey OGWKCGZFUXNPDA-XQKSVPLYSA-N
Search UniChem for chemicals with the same backbone OGWKCGZFUXNPDA
Wikipedia Vincristine
Comments
A pan tubulin inhibitor, isolated from Catharanthus roseus (the Madagascar periwinkle, formerly Vinca rosea). Marketed formulations contain vincristine sulfate (PubChem CID 249332).