phenoxybenzamine

Ligand id: 7268

Name: phenoxybenzamine

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Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 1
Hydrogen bond donors 0
Rotatable bonds 8
Topological polar surface area 12.47
Molecular weight 303.14
XLogP 6.55
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes (FDA (1953))
IUPAC Name
benzyl(2-chloroethyl)(1-phenoxypropan-2-yl)amine
International Nonproprietary Names
INN number INN
608 phenoxybenzamine
Synonyms
Dibenzyline® | phenoxybenzamine hydrochloride
Database Links
CAS Registry No. 59-96-1
ChEMBL Ligand CHEMBL753
DrugBank Ligand DB00925
GtoPdb PubChem SID 178103842
PubChem CID 4768
Search Google for chemical match using the InChIKey QZVCTJOXCFMACW-UHFFFAOYSA-N
Search Google for chemicals with the same backbone QZVCTJOXCFMACW
Search PubMed clinical trials phenoxybenzamine
Search PubMed titles phenoxybenzamine
Search PubMed titles/abstracts phenoxybenzamine
Search UniChem for chemical match using the InChIKey QZVCTJOXCFMACW-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone QZVCTJOXCFMACW
Wikipedia Phenoxybenzamine
Comments
Phenoxybenzamine is a non-selective, irreversible alpha blocker (α-adrenoceptor antagonist).