promethazine

Ligand id: 7282

Name: promethazine

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Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 2
Hydrogen bond donors 0
Rotatable bonds 3
Topological polar surface area 31.78
Molecular weight 284.13
XLogP 4.46
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes (FDA (1951))
IUPAC Name
dimethyl[1-(10H-phenothiazin-10-yl)propan-2-yl]amine
International Nonproprietary Names
INN number INN
516 promethazine
Synonyms
Phenergan® | Sominex®
Database Links
CAS Registry No. 60-87-7
ChEMBL Ligand CHEMBL643
DrugBank Ligand DB01069
GtoPdb PubChem SID 178103856
PubChem CID 4927
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Wikipedia Promethazine
Comments
This drug is a first-generation antihistamine with strong sedative and weak antipsychotic effects. Additional properties include antiemetic and anticholinergic actions.