florbetapir

Ligand id: 7344

Name: florbetapir    

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 12
Topological polar surface area 52.61
Molecular weight 360.18
XLogP 4.38
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes (FDA (2012))
IUPAC Name
4-[(E)-2-[6-(2-{2-[2-(18F)fluoroethoxy]ethoxy}ethoxy)pyridin-3-yl]ethenyl]-N-methylaniline
International Nonproprietary Names
INN number INN
9193 florbetapir (18F)
Synonyms
AMYViD® | AV-45 | florbetapir (18F)
Database Links
CAS Registry No. 956103-76-7 (source: SciFinder)
ChEMBL Ligand CHEMBL1774461
PubChem CID 24822371
Search Google for chemical match using the InChIKey YNDIAUKFXKEXSV-CRYLGTRXSA-N
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Search PubMed clinical trials florbetapir
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Search UniChem for chemical match using the InChIKey YNDIAUKFXKEXSV-CRYLGTRXSA-N
Search UniChem for chemicals with the same backbone YNDIAUKFXKEXSV
Wikipedia Florbetapir
Comments
Florbetapir F18 is a molecular imaging agent (diagnostic radiopharmaceutical) that binds to β-amyloid aggregates in Alzheimer's brains.