Ligand id: 7344

Name: florbetapir    

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 12
Topological polar surface area 52.61
Molecular weight 360.18
XLogP 4.38
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

View interactive charts of activity data from GtoPdb and ChEMBL (where available) across species

Selectivity at ligand targets
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Affinity Units Concentration range (M) Reference
amyloid β Hs None Binding 8.5 pKi - 2
pKi 8.5 (Ki 2.87x10-9 M) PET imaging agent for Aβ plaques in brain [2]