AZD7762

Ligand id: 7713

Name: AZD7762

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 6
Hydrogen bond donors 4
Rotatable bonds 6
Topological polar surface area 124.49
Molecular weight 362.12
XLogP 2.02
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
3-(carbamoylamino)-5-(3-fluorophenyl)-N-[(3S)-piperidin-3-yl]thiophene-2-carboxamide
Synonyms
AZD 7762 | AZD-7762
Database Links
CAS Registry No. 860352-01-8
ChEMBL Ligand CHEMBL2041933
PubChem CID 11152667
RCSB PDB Ligand YDJ
Search Google for chemical match using the InChIKey IAYGCINLNONXHY-LBPRGKRZSA-N
Search Google for chemicals with the same backbone IAYGCINLNONXHY
Search UniChem for chemical match using the InChIKey IAYGCINLNONXHY-LBPRGKRZSA-N
Search UniChem for chemicals with the same backbone IAYGCINLNONXHY
SynPHARM 80208 (in complex with checkpoint kinase 1)
Comments
AZD7762 was developed as an inhibitor of the checkpoint kinases, Chk1 and Chk2 [1], and was investigated as a therapeutic for solid and haematological malignancies. This compound is now included in AstaZeneca's Open Innovation Pharmacology Toolbox.