evocalcet

Ligand id: 9042

Name: evocalcet

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 6
Topological polar surface area 52.57
Molecular weight 374.2
XLogP 6.67
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
2-[4-[(3S)-3-[[(1R)-1-naphthalen-1-ylethyl]amino]pyrrolidin-1-yl]phenyl]acetic acid
International Nonproprietary Names
INN number INN
10098 evocalcet
Synonyms
KHK-7580 | MT-4580
Database Links
CAS Registry No. 870964-67-3 (source: WHO INN record)
GtoPdb PubChem SID 315661127
PubChem CID 71242808
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Search UniChem for chemical match using the InChIKey RZNUIYPHQFXBAN-XLIONFOSSA-N
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Comments
Evocalcet is an investigational calcium-sensing receptor (CASR) agonist, or calcimimetic. CASR is a G protein-coupled receptor.
This compound is claimed in patent US8362274 [1].