Available chemical structures for EP4 receptor agonists

PGE1
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Targets
DP1 receptor; EP1 receptor; EP2 receptor; EP3 receptor; EP4 receptor; IP receptor
11-deoxy-PGE1
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Targets
EP2 receptor; EP3 receptor; EP4 receptor
L902688
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Targets
EP4 receptor
CP734432
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Targets
EP4 receptor
PGD2
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Targets
DP1 receptor; DP2 receptor; EP1 receptor; EP2 receptor; EP3 receptor; EP4 receptor; FP receptor; IP receptor; TP receptor
MB-28767
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Targets
EP1 receptor; EP2 receptor; EP3 receptor; EP4 receptor; FP receptor; TP receptor
ONO-AE1-329
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Targets
EP2 receptor; EP3 receptor; EP4 receptor
treprostinil
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Targets
DP1 receptor; EP1 receptor; EP2 receptor; EP3 receptor; EP4 receptor; IP receptor
iloprost
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Targets
DP1 receptor; EP1 receptor; EP2 receptor; EP3 receptor; EP4 receptor; FP receptor; IP receptor
PGE2
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Targets
DP1 receptor; DP2 receptor; EP1 receptor; EP2 receptor; EP3 receptor; EP4 receptor; FP receptor; IP receptor; OATP1A2; Organic anion transporter 2; Organic cation transporter 1; Organic cation transporter 2; TP receptor
PGF2α
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Targets
DP1 receptor; DP2 receptor; EP1 receptor; EP2 receptor; EP3 receptor; EP4 receptor; FP receptor; IP receptor; Organic cation transporter 1; TP receptor
[3H]PGE2
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Targets
DP1 receptor; EP1 receptor; EP2 receptor; EP3 receptor; EP4 receptor; OATP2A1; OATP3A1
KMN-159
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Targets
EP4 receptor
rivenprost
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Targets
EP2 receptor; EP3 receptor; EP4 receptor
ONO-AE1-437
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Targets
EP4 receptor
11-deoxy-PGE2
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Targets
EP4 receptor
TCS 2510
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Targets
EP4 receptor
13,14-dihydro-PGE1
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Targets
EP4 receptor
L-161,982 (EP4A)
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Targets
EP4 receptor
misoprostol (free acid form)
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Targets
EP2 receptor; EP3 receptor; EP4 receptor
19(R)-OH-PGE2
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Targets
EP2 receptor; EP4 receptor
cicaprost
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Targets
EP1 receptor; EP2 receptor; EP3 receptor; EP4 receptor; IP receptor
enprostil
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Targets
EP1 receptor; EP3 receptor; EP4 receptor; FP receptor
16,16-dimethyl-PGE2
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Targets
EP2 receptor; EP3 receptor; EP4 receptor
1-OH-PGE1
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Targets
EP4 receptor
carbacyclin
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Targets
DP1 receptor; EP1 receptor; EP2 receptor; EP3 receptor; EP4 receptor; FP receptor; IP receptor; TP receptor
U46619
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Targets
DP1 receptor; DP2 receptor; EP1 receptor; EP2 receptor; EP3 receptor; EP4 receptor; FP receptor; TP receptor
MRE-269
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Targets
EP2 receptor; EP4 receptor; IP receptor
misoprostol (methyl ester)
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Targets
EP2 receptor; EP3 receptor; EP4 receptor
beraprost
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Targets
EP3 receptor; EP4 receptor; IP receptor
PGI2
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Targets
DP1 receptor; DP2 receptor; EP1 receptor; EP2 receptor; EP3 receptor; EP4 receptor; FP receptor; IP receptor; TP receptor
butaprost (free acid form)
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Targets
DP1 receptor; EP2 receptor; EP3 receptor; EP4 receptor; IP receptor; TP receptor
17-phenyl-ω-trinor-PGE2
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Targets
EP1 receptor; EP2 receptor; EP3 receptor; EP4 receptor

Please note that chemical structures may not be available for all agonists at this target. For more details please email us.