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Organic anion transporters (OATs) C

Unless otherwise stated all data on this page refer to the human proteins. Gene information is provided for human (Hs), mouse (Mm) and rat (Rn).

Overview

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Organic anion transporters (OATs) are non-selective transporters prominent in the kidney, placenta and blood-brain barrier.

Transporters

1026
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OAT1 (Organic anion transporter 1 / SLC22A6) C Show summary » More detailed page go icon to follow link

OAT2 (Organic anion transporter 2 / SLC22A7) C Show summary »

Target Id 1026
Nomenclature Organic anion transporter 2
Systematic nomenclature SLC22A7
Common abbreviation OAT2
Previous and unofficial names Novel liver transporter | NLT | solute carrier family 22 member 7 | solute carrier family 22 (organic anion transporter), member 7 | solute carrier family 22 (organic anion transporter)
Genes SLC22A7 (Hs), Slc22a7 (Mm), Slc22a7 (Rn)
Ensembl ID ENSG00000137204 (Hs), ENSMUSG00000067144 (Mm), ENSRNOG00000018420 (Rn)
UniProtKB AC Q9Y694 (Hs), Q91WU2 (Mm), Q5RLM2 (Rn)
Bioparadigms SLC Tables SLC22A7 (Hs)
RESOLUTE SLC22A7 (Hs)
Substrates
PGE2
aminohippuric acid
non-steroidal anti-inflammatory drugs
Stoichiometry Unknown

OAT3 (Organic anion transporter 3 / SLC22A8) C Show summary » More detailed page go icon to follow link

Organic anion transporter 4 / SLC22A11 C Show summary » More detailed page go icon to follow link

OAT4 (Organic anion transporter 7 / SLC22A9) C Show summary »

Further reading

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References

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NC-IUPHAR subcommittee and family contributors

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How to cite this family page

Database page citation (select format):

Concise Guide to PHARMACOLOGY citation:

Alexander SPH, Fabbro D, Kelly E, Mathie AA, Peters JA, Veale EL, Armstrong JF, Faccenda E, Harding SD, Davies JA et al. (2023) The Concise Guide to PHARMACOLOGY 2023/24: Transporters. Br J Pharmacol. 180 Suppl 2:S374-469.