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Target not currently curated in GtoImmuPdb
Target id: 1030
Nomenclature: Organic anion transporter 4
Systematic Nomenclature: SLC22A11
Gene and Protein Information  |
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| Species | TM | AA | Chromosomal Location | Gene Symbol | Gene Name | Reference |
| Human | 12 | 550 | 11q13.1 | SLC22A11 | solute carrier family 22 member 11 | |
| Previous and Unofficial Names |
| OAT4 | solute carrier family 22 (organic anion/urate transporter), member 11 |
| Database Links |
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| Specialist databases | |
| Bioparadigms SLC Tables | SLC22A11 (Hs) |
| RESOLUTE | SLC22A11 (Hs) |
| Other databases | |
| Alphafold | Q9NSA0 (Hs) |
| ChEMBL Target | CHEMBL2073677 (Hs) |
| DrugBank Target | Q9NSA0 (Hs) |
| Ensembl Gene | ENSG00000168065 (Hs) |
| Entrez Gene | 55867 (Hs) |
| Human Protein Atlas | ENSG00000168065 (Hs) |
| KEGG Gene | hsa:55867 (Hs) |
| OMIM | 607097 (Hs) |
| Pharos | Q9NSA0 (Hs) |
| UniProtKB | Q9NSA0 (Hs) |
| Wikipedia | SLC22A11 (Hs) |
| Substrates and Reaction Kinetics |
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| Stoichiometry |
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| Unknown | |
Download all structure-activity data for this target as a CSV file 
| Inhibitors | |||||||||||||||||||||||||||||||||||||||||||||||||||
| Key to terms and symbols | View all chemical structures | Click column headers to sort | |||||||||||||||||||||||||||||||||||||||||||||||||
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1. Cha SH, Sekine T, Kusuhara H, Yu E, Kim JY, Kim DK, Sugiyama Y, Kanai Y, Endou H. (2000) Molecular cloning and characterization of multispecific organic anion transporter 4 expressed in the placenta. J Biol Chem, 275 (6): 4507-12. [PMID:10660625]
2. Nigam SK, Bhatnagar V. (2018) The systems biology of uric acid transporters: the role of remote sensing and signaling. Curr Opin Nephrol Hypertens, 27 (4): 305-313. [PMID:29847376]
3. Takeda M, Babu E, Narikawa S, Endou H. (2002) Interaction of human organic anion transporters with various cephalosporin antibiotics. Eur J Pharmacol, 438 (3): 137-42. [PMID:11909604]
