quinidine

Ligand id: 2342

Name: quinidine

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 4
Topological polar surface area 45.59
Molecular weight 324.18
XLogP 2.66
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Natural product or derivative
Approved drug? Yes (source: FDA (1950))
IUPAC Name
(S)-[(4S,5R,7R)-5-ethenyl-1-azabicyclo[2.2.2]octan-7-yl]-(6-methoxyquinolin-4-yl)methanol
Synonyms
Quinaglute®
Quinidex®
quinidine hydrochloride
Database Links
BindingDB Ligand 50121975
CAS Registry No. 56-54-2
ChEBI CHEBI:127150
ChEMBL Ligand CHEMBL1294
DrugBank Ligand DB00908
PharmGKB Drug PA451209
PubChem CID 441074
RCSB PDB Ligand QDN
Search Google for chemical match using the InChIKey LOUPRKONTZGTKE-LHHVKLHASA-N
Search Google for chemicals with the same backbone LOUPRKONTZGTKE
Wikipedia Quinidine
Comments
Quinidine is a stereoisomer of quinine. It acts as a class I antiarrhythmic agent, blocking the fast inward sodium current (INa).