ziprasidone

Ligand id: 59

Name: ziprasidone

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Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 4
Topological polar surface area 76.71
Molecular weight 412.11
XLogP 3.46
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes (FDA (2001))
IUPAC Name
5-[2-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]ethyl]-6-chloro-1,3-dihydroindol-2-one
International Nonproprietary Names
INN number INN
7155 ziprasidone
Synonyms
CP-88059 | CP-88059-27 | CP-880591 | CP-8805927 | Geodon®
Database Links
BindingDB Ligand 50048803
CAS Registry No. 146939-27-7
ChEBI CHEBI:10119
ChEMBL Ligand CHEMBL708
DrugBank Ligand DB00246
PubChem CID 60854
Search Google for chemical match using the InChIKey MVWVFYHBGMAFLY-UHFFFAOYSA-N
Search Google for chemicals with the same backbone MVWVFYHBGMAFLY
Search PubMed clinical trials ziprasidone
Search PubMed titles ziprasidone
Search PubMed titles/abstracts ziprasidone
Search UniChem for chemical match using the InChIKey MVWVFYHBGMAFLY-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone MVWVFYHBGMAFLY
Wikipedia Ziprasidone
Comments
Ziprasidone is a monoaminergic antagonist with affinity for a range of receptors including dopamine receptors, alpha 1 and 2 adrenoceptors, the histamine H1 receptor, and serotonin 5-HT receptors. Marketed formulations may contain ziprasidone hydrochloride (PubChem CID 219099).