dioctanoylglycerol pyrophosphate

Ligand id: 2916

Name: dioctanoylglycerol pyrophosphate

Abbreviated name: DGPP

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 11
Hydrogen bond donors 3
Rotatable bonds 22
Topological polar surface area 185.51
Molecular weight 504.19
XLogP 3.34
No. Lipinski's rules broken 2

Molecular properties generated using the CDK

View interactive charts of activity data from ChEMBL and GtoPdb across species (New!)

Selectivity at human GPCRs
Key to terms and symbols Click column headers to sort
Target Type Action Affinity Units Concentration range (M) Reference
LPA3 receptor Antagonist Antagonist 5.5 – 7.0 pKi - 1,4
pKi 5.5 – 7.0 (Ki 3.33x10-6 M) [1,4]
LPA1 receptor Antagonist Antagonist 5.2 – 5.2 pKi - 1-2
pKi 5.2 – 5.2 (Ki 7x10-6 – 6.6x10-6 M) [1-2]
LPA3 receptor Agonist Agonist 7.0 pIC50 - 1
pIC50 7.0 (IC50 1.06x10-7 M) [1]
GPR87 Antagonist Antagonist - - - 5
[5]
P2RY10 Antagonist Antagonist - - - 3
[3]