miglitol

Ligand id: 4842

Name: miglitol

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 6
Hydrogen bond donors 5
Rotatable bonds 3
Topological polar surface area 104.39
Molecular weight 207.11
XLogP -2.26
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

View interactive charts of activity data from ChEMBL and GtoPdb across species (New!)

Transporters Moving this Compound Across a Lipid Membrane
Transporter EC number Reaction Reference
Low affinity sodium-glucose cotransporter 4
Selectivity at human enzymes
Key to terms and symbols Click column headers to sort
Target Type Action Affinity Units Concentration range (M) Reference
maltase-glucoamylase Inhibitor Inhibition 6.0 pKi - 3
pKi 6.0 (Ki 1x10-6 M) [3]
Description: Inhibition of human recombinant N-terminal subunit of maltase-glucoamylase after 60 mins by glucose oxidase assay
glucosidase alpha, acid Inhibitor Inhibition 6.5 pIC50 - 2
pIC50 6.5 (IC50 3.5x10-7 M) [2]
Selectivity at mouse enzymes
Key to terms and symbols Click column headers to sort
Target Type Action Affinity Units Concentration range (M) Reference
maltase-glucoamylase Inhibitor Inhibition 6.0 – 6.7 pKi - 1
pKi 6.0 – 6.7 (Ki 1x10-6 – 2.11x10-7 M) Inhibition across MGAM catalytic subunits [1]