[3H]9-cis-retinoic acid

Ligand id: 5383

Name: [3H]9-cis-retinoic acid    

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 5
Topological polar surface area 37.3
Molecular weight 300.21
XLogP 6.25
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

View interactive charts of activity data from ChEMBL and GtoPdb across species (New!)

Selectivity at mouse nuclear hormone receptors
Key to terms and symbols Click column headers to sort
Target Type Action Affinity Units Concentration range (M) Reference
Retinoic acid receptor-α Agonist Full agonist 9.6 pKd - 1
pKd 9.6 (Kd 2.4x10-10 M) [1]
Retinoic acid receptor-β Agonist Full agonist 9.4 pKd - 1
pKd 9.4 (Kd 4x10-10 M) [1]
Retinoic acid receptor-γ Agonist Full agonist 9.2 pKd - 1
pKd 9.2 (Kd 7x10-10 M) [1]
Retinoid X receptor-γ Agonist Full agonist 7.9 pKd - 1
pKd 7.9 (Kd 1.41x10-8 M) [1]
Retinoid X receptor-α Agonist Full agonist 7.8 pKd - 1
pKd 7.8 (Kd 1.57x10-8 M) [1]
Retinoid X receptor-β Agonist Full agonist 7.7 pKd - 1
pKd 7.7 (Kd 1.83x10-8 M) [1]