nepafenac

Ligand id: 7564

Name: nepafenac

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Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 4
Topological polar surface area 86.18
Molecular weight 254.11
XLogP 3.16
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

View interactive charts of activity data from ChEMBL and GtoPdb across species (New!)

Bioactivity Comments
There is animal model data to support nepafenac's effectiveness as an antiinflammatory agent [1,3-5]. But note that as these are reports of in vivo studies, the drug effect will be caused by the active metabolite, amfenac.