enclomiphene

Ligand id: 7619

Name: enclomiphene

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 1
Hydrogen bond donors 0
Rotatable bonds 9
Topological polar surface area 12.47
Molecular weight 405.19
XLogP 9.85
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

View interactive charts of activity data from ChEMBL and GtoPdb across species (New!)

Bioactivity Comments
DrugMatrix in vitro pharmacology assay data provides an IC50 value of 4.56nM for enclomiphene at the estrogen receptor alpha [1]. But as we have been unable to find any other publicly available affinity data for this drug at its proposed molecular target to substantiate this MMOA, we have not tagged a primary drug target.