Ligand id: 7619

Name: enclomiphene

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 1
Hydrogen bond donors 0
Rotatable bonds 9
Topological polar surface area 12.47
Molecular weight 405.19
XLogP 9.85
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

1. Auerbach SS, DrugMatrix® and ToxFX® Coordinator National Toxicology Program. 
National Toxicology Program: Dept of Health and Human Services.
Accessed on 02/05/2014. Modified on 02/05/2014. DrugMatrix, https://ntp.niehs.nih.gov/drugmatrix/index.html
2. Hill S, Arutchelvam V, Quinton R. (2009)
Enclomiphene, an estrogen receptor antagonist for the treatment of testosterone deficiency in men.
IDrugs, 12 (2): 109-19. [PMID:19204885]
3. Ioannidou-Kadis S, Wright PJ, Neely RD, Quinton R. (2006)
Complete reversal of adult-onset isolated hypogonadotropic hypogonadism with clomiphene citrate.
Fertil. Steril., 86 (5): 1513.e5-9. [PMID:17070201]