cis-JB253

Ligand id: 7787

Name: cis-JB253

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 8
Hydrogen bond donors 2
Rotatable bonds 10
Topological polar surface area 111.61
Molecular weight 457.21
XLogP 6.81
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

Bioactivity Comments
In common with other sulfonylurea compounds, cis-JB253 depolarizes ATP-sensitive potassiun channels on pancreatic B-cells [1].