atezolizumab

Ligand id: 7990

Name: atezolizumab

View interactive charts of activity data from GtoPdb and ChEMBL (where available) across species

Bioactivity Comments
The development and use of atezolizumab is claimed in patent US8217149 [1]. The actual antibody clone selected as the lead is not disclosed in the patent, so affinity data in the table below is representative of preferred antibodies noted in the patent document, for example YW243.55.S70.
Selectivity at ligand targets
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Affinity Units Concentration range (M) Reference
programmed cell death 1 ligand 1 Hs Antibody Binding 9.0 – 10.0 pKd - 1
pKd 9.0 – 10.0 (Kd 1x10-9 – 1x10-10 M) [1]