Ligand id: 1958

Name: bimatoprost

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Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 4
Rotatable bonds 13
Topological polar surface area 89.79
Molecular weight 415.27
XLogP 5.18
No. Lipinski's rules broken 2

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
Used in the management of open angle glaucoma or ocular hypertension.
Mechanism Of Action and Pharmacodynamic Effects
Bimatoprost decreases the pressure within the eye by mimicking the action of prostaglandin PGF in increasing the outflow of aqueous humor from the eyeball.