Synonyms: EYEOO1 | Macugen® | NX183 | pegaptanib sodium
pegaptanib is an approved drug (FDA (2004), EMA (2006))
Compound class:
Synthetic organic
Comment: Pegaptanib is a RNA oligonucleotide aptamer that cts as a vascular endothelial growth factor A antagonist, anti-angiogenic agent.
It is a 28-mer RNA aptamer that is covalently linked to two branched 20-kD polyethylene glycol (PEG) chains. |
No information available. |
Summary of Clinical Use |
Used to treat neovascular (wet) age-related macular degeneration |
External links |
For extended ADME data see the following: Electronic Medicines Compendium (eMC) Drugs.com European Medicines Agency (EMA) |