phenacemide

Ligand id: 7265

Name: phenacemide

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 3
Rotatable bonds 3
Topological polar surface area 76.67
Molecular weight 178.07
XLogP 2.98
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
Used to treat complex partial epileptic seizures [1].
Mechanism Of Action and Pharmacodynamic Effects
This drug blocks sodium channels and prevents the hypersynchronisation of neuronal firing which is believed to cause seizures [2-3]. The genes and proteins SNC1A-SNC11A are listed in this database in the voltage-gated sodium channels section.