Ligand id: 2858

Name: testosterone

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Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 0
Topological polar surface area 37.3
Molecular weight 288.21
XLogP 3.63
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

1. Bhatnagar AS, Häusler A, Schieweck K, Lang M, Bowman R. (1990)
Highly selective inhibition of estrogen biosynthesis by CGS 20267, a new non-steroidal aromatase inhibitor.
J. Steroid Biochem. Mol. Biol., 37 (6): 1021-7. [PMID:2149502]
2. Fang H, Tong W, Branham WS, Moland CL, Dial SL, Hong H, Xie Q, Perkins R, Owens W, Sheehan DM. (2003)
Study of 202 natural, synthetic, and environmental chemicals for binding to the androgen receptor.
Chem. Res. Toxicol., 16 (10): 1338-58. [PMID:14565775]
3. Plourde PV, Dyroff M, Dukes M. (1994)
Arimidex: a potent and selective fourth-generation aromatase inhibitor.
Breast Cancer Res. Treat., 30 (1): 103-11. [PMID:7949201]