Ligand id: 4789

Name: 5-fluorouracil

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 0
Topological polar surface area 58.2
Molecular weight 130.02
XLogP -0.59
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

1. Yamamoto S, Inoue K, Murata T, Kamigaso S, Yasujima T, Maeda JY, Yoshida Y, Ohta KY, Yuasa H. (2010)
Identification and functional characterization of the first nucleobase transporter in mammals: implication in the species difference in the intestinal absorption mechanism of nucleobases and their analogs between higher primates and other mammals.
J. Biol. Chem., 285 (9): 6522-31. [PMID:20042597]