Ligand id: 5046

Name: pertuzumab

1. Adams CW, Allison DE, Flagella K, Presta L, Clarke J, Dybdal N, McKeever K, Sliwkowski MX. (2006)
Humanization of a recombinant monoclonal antibody to produce a therapeutic HER dimerization inhibitor, pertuzumab.
Cancer Immunol. Immunother., 55 (6): 717-27. [PMID:16151804]
2. Badache A, Hynes NE. (2004)
A new therapeutic antibody masks ErbB2 to its partners.
Cancer Cell, 5 (4): 299-301. [PMID:15093533]
3. Ferguson KM. (2004)
Active and inactive conformations of the epidermal growth factor receptor.
Biochem. Soc. Trans., 32 (Pt 5): 742-5. [PMID:15494003]
4. Kao Y-H, Vanderlaan M. (2006)
Her2 antibody composition.
Patent number: WO2006033700. Assignee: Genentech Inc.. Priority date: 22/07/2004. Publication date: 30/04/2010.