Ligand id: 5046

Name: pertuzumab

No information available.
Summary of Clinical Use
Used for the treatment of HER2 overexpressing breast cancer, in combination with trastuzumab and docetaxel.
Mechanism Of Action and Pharmacodynamic Effects
Binds to the ERBB2 (HER2) receptor and prevents dimerisation with other HER receptors [1,3]. This reduces activation of downstream signalling pathways [2] and ultimately slows cancer cell growth.
External links