Ligand id: 5046

Name: pertuzumab

View interactive charts of activity data from GtoPdb and ChEMBL (where available) across species

Selectivity at catalytic receptors
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Target Sp. Type Action Affinity Units Concentration range (M) Reference
erb-b2 receptor tyrosine kinase 2 Hs Antibody Inhibition >8.0 pIC50 - 4
pIC50 >8.0 (IC50 <1x10-8 M) [4]
Description: Preferred value for inhibition of heregulin β1 binding to MCF7 cells.
Ligand mentioned in the following text fields