Ligand id: 8455

Name: daprodustat

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 9
Hydrogen bond donors 2
Rotatable bonds 6
Topological polar surface area 124.09
Molecular weight 393.19
XLogP 1.68
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

1. Bouchie A. (2013)
First-in-class anemia drug takes aim at Amgen's dominion.
Nat. Biotechnol.31 (11): 948-9. [PMID:24213751]
2. Forristal CE, Levesque JP. (2014)
Targeting the hypoxia-sensing pathway in clinical hematology.
Stem Cells Transl Med3 (2): 135-40. [PMID:24371328]