trastuzumab

Ligand id: 5082

Name: trastuzumab

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Classification
Compound class Antibody
Approved drug? Yes (FDA (1998), EMA (2000))
International Nonproprietary Names
INN number INN
7637 trastuzumab
Synonyms
D5v8 | Herceptin® | R-597
Database Links
Specialist databases
IMGT/mAb-DB 97
Other databases
PubChem SID 178101775
Search PubMed clinical trials trastuzumab
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Wikipedia Trastuzumab
Comments
Trastuzumab is a humanized IgG1κ monoclonal antibody targeting HER2.
Annotated peptide sequences for this antibody are available from its IMGT/mAb-DB record.

Biosimilar drugs: Mylan laboratories Inc. and Biocon Limited are partnering the marketing of MYL-1401O (Hertraz®, Canmab®) a biosimilar already approved in India. A Biologics License Application (BLA) for MYL-1401O has been accepted by the FDA, and it is also under review by the EMA. Herzum® (CT-P6; Celltrion Inc.) is approved in Korea. These biosimilars are all approved for the same clinical indications as the reference drug. CT-P6 as Credima® is pre-registered with the EMA and SB3 is in Samsung Bioepis' development pipeline.