rivaroxaban

Ligand id: 6388

Name: rivaroxaban

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Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 8
Hydrogen bond donors 1
Rotatable bonds 6
Topological polar surface area 116.42
Molecular weight 435.07
XLogP 1.87
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes (EMA (2008), FDA (2011))
IUPAC Name
5-chloro-N-[[(5S)-2-oxo-3-[4-(3-oxomorpholin-4-yl)phenyl]-1,3-oxazolidin-5-yl]methyl]thiophene-2-carboxamide
International Nonproprietary Names
INN number INN
8428 rivaroxaban
Synonyms
BAY 59-7939 | Xarelto®
Database Links
CAS Registry No. 366789-02-8 (source: ChEBI)
ChEBI CHEBI:68579
ChEMBL Ligand CHEMBL198362
PubChem CID 9875401
RCSB PDB Ligand RIV
Search Google for chemical match using the InChIKey KGFYHTZWPPHNLQ-AWEZNQCLSA-N
Search Google for chemicals with the same backbone KGFYHTZWPPHNLQ
Search PubMed clinical trials rivaroxaban
Search PubMed titles rivaroxaban
Search PubMed titles/abstracts rivaroxaban
Search UniChem for chemical match using the InChIKey KGFYHTZWPPHNLQ-AWEZNQCLSA-N
Search UniChem for chemicals with the same backbone KGFYHTZWPPHNLQ
SynPHARM 78509 (in complex with coagulation factor X)
Wikipedia Rivaroxaban
Comments
First in class orally active direct factor Xa inhibitor.