Ligand id: 8882

Name: enoxacin

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 7
Hydrogen bond donors 2
Rotatable bonds 3
Topological polar surface area 85.77
Molecular weight 320.13
XLogP 0.75
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

View interactive charts of activity data from GtoPdb and ChEMBL (where available) across species

Selectivity at transporters
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Affinity Units Concentration range (M) Reference
V-type ATPase V1 motor B2 subunit Hs Inhibitor Inhibition 5.0 pIC50 - 2
pIC50 5.0 (IC50 1x10-5 M) [2]
Description: Measuring inhibition of the interaction between the profilin-like domain of the B2 subunit and F-actin.