Ligand id: 7882

Name: crenolanib

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 6
Hydrogen bond donors 1
Rotatable bonds 5
Topological polar surface area 78.43
Molecular weight 443.23
XLogP 3.93
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Immunopharmacology Comments
Included in GtoImmuPdb based on its clinical potential.
Immunopharmacology Disease
Disease X-Refs Comment References
Acute myeloid leukemia Disease Ontology: DOID:9119
OMIM: 601626
Orphanet: ORPHA519
Phase 3 clinical candidate for FLT3 mutation positive relapsed/refractory AML.