Available chemical structures for glycogen synthase kinase 3 beta inhibitors

CHIR-98014
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Targets
glycogen synthase kinase 3 alpha; glycogen synthase kinase 3 beta
alsterpaullone 2-cyanoethyl
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Targets
cyclin dependent kinase 1; glycogen synthase kinase 3 beta
LY2090314
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Targets
glycogen synthase kinase 3 beta
GSK-3β inhibitor 3 [PMID: 25845281]
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Targets
glycogen synthase kinase 3 beta
RGB-286638
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Targets
Janus kinase 2; cyclin dependent kinase 1; cyclin dependent kinase 2; cyclin dependent kinase 3; cyclin dependent kinase 4; cyclin dependent kinase 5; cyclin dependent kinase 6; cyclin dependent kinase 7; cyclin dependent kinase 9; fms related receptor tyrosine kinase 3; glycogen synthase kinase 3 beta; mitogen-activated protein kinase 9; mitogen-activated protein kinase kinase kinase 7
alsterpaullone
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Targets
cyclin dependent kinase 1; glycogen synthase kinase 3 beta
GSK-3 inhibitor IX
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Targets
cyclin dependent kinase 1; cyclin dependent kinase 5; glycogen synthase kinase 3 alpha; glycogen synthase kinase 3 beta
laduviglusib
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Targets
cyclin dependent kinase 1; glycogen synthase kinase 3 alpha; glycogen synthase kinase 3 beta; mitogen-activated protein kinase 1
SB 216763
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Targets
glycogen synthase kinase 3 alpha; glycogen synthase kinase 3 beta
GSK-3 inhibitor X
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Targets
glycogen synthase kinase 3 alpha; glycogen synthase kinase 3 beta
GNF4877
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Targets
dual specificity tyrosine phosphorylation regulated kinase 1A; glycogen synthase kinase 3 beta
compound 2 [PMID: 22560567]
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Targets
CDC like kinase 1; Casein kinase 2; Pim-1 proto-oncogene, serine/threonine kinase; cell division cycle 7; glycogen synthase kinase 3 beta
1-azakenpaullone
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Targets
cyclin dependent kinase 1; cyclin dependent kinase 5; glycogen synthase kinase 3 beta
indirubin-3'-monoxime
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Targets
glycogen synthase kinase 3 beta
kenpaullone
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Targets
cyclin dependent kinase 1; cyclin dependent kinase 2; cyclin dependent kinase 5; glycogen synthase kinase 3 beta
compound 52 [PMID: 9677190]
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Targets
cyclin dependent kinase 1; glycogen synthase kinase 3 beta
TWS119
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Targets
glycogen synthase kinase 3 beta
SB-415286
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Targets
glycogen synthase kinase 3 alpha; glycogen synthase kinase 3 beta
IM-12
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Targets
glycogen synthase kinase 3 beta
compound 2f [Jiang et al., 2018]
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Targets
acetylcholinesterase (Yt blood group); glycogen synthase kinase 3 beta
voruciclib
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Targets
LIM domain kinase 1; Pim-1 proto-oncogene, serine/threonine kinase; casein kinase 1 gamma 1; cyclin dependent kinase 1; cyclin dependent kinase 2; cyclin dependent kinase 4; cyclin dependent kinase 5; cyclin dependent kinase 6; cyclin dependent kinase 8; cyclin dependent kinase 9; dual specificity tyrosine phosphorylation regulated kinase 1B; glycogen synthase kinase 3 alpha; glycogen synthase kinase 3 beta; mitogen-activated protein kinase kinase 2
gomisin N
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Targets
glycogen synthase kinase 3 beta
compound 89S [PMID: 19115845]
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Targets
TAO kinase 3; cell division cycle 7; cyclin dependent kinase 1; cyclin dependent kinase 2; cyclin dependent kinase 9; glycogen synthase kinase 3 beta; serine/threonine-protein kinase NIM1
compound 4g [PMID: 2680437]
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Targets
glycogen synthase kinase 3 beta
compound 5 [PMID: 19338355]
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Targets
glycogen synthase kinase 3 beta
compound 5b [PMID: 24900464]
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Targets
Casein kinase 2; dual specificity tyrosine phosphorylation regulated kinase 2; glycogen synthase kinase 3 beta; homeodomain interacting protein kinase 2
GSK-3beta inhibitor II
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Targets
glycogen synthase kinase 3 beta
isogranulatimide
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Targets
checkpoint kinase 1; checkpoint kinase 2; glycogen synthase kinase 3 beta
7-hydroxystaurosporine
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Targets
3-phosphoinositide dependent protein kinase 1; LCK proto-oncogene, Src family tyrosine kinase; checkpoint kinase 1; checkpoint kinase 2; cyclin dependent kinase 1; glycogen synthase kinase 3 beta; microtubule affinity regulating kinase 1; mitogen-activated protein kinase 14; protein kinase A; protein kinase C alpha; protein kinase C beta; protein kinase C delta; protein kinase C epsilon; protein kinase C gamma
BX-795
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Targets
3-phosphoinositide dependent protein kinase 1; TANK binding kinase 1; aurora kinase B; checkpoint kinase 1; cyclin dependent kinase 2; glycogen synthase kinase 3 beta; inhibitor of nuclear factor kappa B kinase subunit epsilon; kinase insert domain receptor; protein kinase A
elraglusib
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Targets
glycogen synthase kinase 3 beta
Cdk/Crk inhibitor
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Targets
cyclin dependent kinase 6; cyclin dependent kinase 7; glycogen synthase kinase 3 beta
Cdk1/5 inhibitor
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Targets
cyclin dependent kinase 1; cyclin dependent kinase 5; glycogen synthase kinase 3 beta
GSK-3beta inhibitor I
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Targets
glycogen synthase kinase 3 beta
GSK2646264
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Targets
Janus kinase 2; LCK proto-oncogene, Src family tyrosine kinase; aurora kinase A; aurora kinase B; glycogen synthase kinase 3 beta; kinase insert domain receptor; leucine rich repeat kinase 2; spleen associated tyrosine kinase
compound 4-3 [PMID: 34027661]
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Targets
glycogen synthase kinase 3 beta
BX-912
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Targets
3-phosphoinositide dependent protein kinase 1; checkpoint kinase 1; cyclin dependent kinase 2; glycogen synthase kinase 3 beta; kinase insert domain receptor; protein kinase A
AZD2858
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Targets
glycogen synthase kinase 3 beta
GSK-3 inhibitor XIII
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Targets
SRC proto-oncogene, non-receptor tyrosine kinase; aurora kinase A; glycogen synthase kinase 3 beta
GSK-3beta inhibitor XI
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Targets
glycogen synthase kinase 3 beta
AZD1080
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Targets
glycogen synthase kinase 3 alpha; glycogen synthase kinase 3 beta
GSK-3beta inhibitor VIII
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Targets
glycogen synthase kinase 3 beta
tideglusib
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Targets
glycogen synthase kinase 3 beta

Please note that chemical structures may not be available for all inhibitors at this target. For more details please email us.