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SLC65 NPC-type cholesterol transporters C

Unless otherwise stated all data on this page refer to the human proteins. Gene information is provided for human (Hs), mouse (Mm) and rat (Rn).


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The SLC65 family of intracellular cholesterol transporters are 13TM membrane proteins. NPC1/SLC65A1 is an intracellular cholesterol transporter, which together with NPC2 (Uniprot ID P61916), allows the accumulation into the cytosol of cholesterol acquired from low density lipoproteins.


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NPC intracellular cholesterol transporter 1 / SLC65A1 C Show summary »

NPC1 like intracellular cholesterol transporter 1 / SLC65A2 C Show summary » More detailed page go icon to follow link

Further reading

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How to cite this family page

Database page citation:

SLC65 NPC-type cholesterol transporters. Accessed on 29/05/2024. IUPHAR/BPS Guide to PHARMACOLOGY,

Concise Guide to PHARMACOLOGY citation:

Alexander SPH, Fabbro D, Kelly E, Mathie AA, Peters JA, Veale EL, Armstrong JF, Faccenda E, Harding SD, Davies JA et al. (2023) The Concise Guide to PHARMACOLOGY 2023/24: Transporters. Br J Pharmacol. 180 Suppl 2:S374-469.