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SLC65 NPC-type cholesterol transporters C

Unless otherwise stated all data on this page refer to the human proteins. Gene information is provided for human (Hs), mouse (Mm) and rat (Rn).


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The SLC65 family of intracellular cholesterol transporters are 13TM membrane proteins. NPC1/SLC65A1 is an intracellular cholesterol transporter, which together with NPC2 (Uniprot ID P61916), allows the accumulation into the cytosol of cholesterol acquired from low density lipoproteins.


NPC intracellular cholesterol transporter 1 / SLC65A1 C Show summary »

NPC1 like intracellular cholesterol transporter 1 / SLC65A2 C Show summary » More detailed page

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How to cite this family page

Database page citation:

SLC65 NPC-type cholesterol transporters. Accessed on 22/09/2020. IUPHAR/BPS Guide to PHARMACOLOGY,

Concise Guide to PHARMACOLOGY citation:

Alexander SPH, Kelly E, Mathie A, Peters JA, Veale EL, Armstrong JF, Faccenda E, Harding SD, Pawson AJ, Sharman JL, Southan C, Davies JA; CGTP Collaborators. (2019) The Concise Guide to PHARMACOLOGY 2019/20: Transporters. Br J Pharmacol. 176 Issue S1: S397-S493.