Acyl-CoA synthetases

Home
Targets
Enzymes
Acyl-CoA synthetases

Unless otherwise stated all data on this page refer to the human proteins. Gene information is provided for human (Hs), mouse (Mm) and rat (Rn).

Overview

Show »« Hide

ACSS2 is a monomeric cytosolic enzyme that catalyses the formation of acetyl-CoA from acetate, CoA, and ATP. It plays a role in the biosynthesis of cholesterol, glucose, and fatty acids. ACSS2 is also a drug target for cancer and neurodegenerative diseases [1].

Enzymes

acyl-CoA synthetase short chain family member 2 Show summary »« Hide summary More detailed page go icon to follow link

Target Id	3128
Nomenclature	acyl-CoA synthetase short chain family member 2
Genes	ACSS2 (Hs)
Ensembl ID	ENSG00000131069 (Hs)
UniProtKB AC	Q9NR19 (Hs)

References

Show »« Hide

How to cite this family page

Database page citation:

Acyl-CoA synthetases. Accessed on 19/04/2024. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/FamilyDisplayForward?familyId=1036.

Concise Guide to PHARMACOLOGY citation:

Alexander SPH, Fabbro D, Kelly E, Mathie AA, Peters JA, Veale EL, Armstrong JF, Faccenda E, Harding SD, Davies JA et al. (2023) The Concise Guide to PHARMACOLOGY 2023/24: Enzymes. Br J Pharmacol. 180 Suppl 2:S289-373.