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Mitofusin proteins

Unless otherwise stated all data on this page refer to the human proteins. Gene information is provided for human (Hs), mouse (Mm) and rat (Rn).


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The mitofusins (MFNs) are mitochondrial GTPases that are essential for regulating mitochondrial clustering and fusion [3]. Defects in MFN protein function are associated with mitochondrial diseases.


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mitofusin 1 Show summary »

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How to cite this family page

Database page citation:

Mitofusin proteins. Accessed on 13/04/2024. IUPHAR/BPS Guide to PHARMACOLOGY,

Concise Guide to PHARMACOLOGY citation:

Alexander SPH, Fabbro D, Kelly E, Mathie AA, Peters JA, Veale EL, Armstrong JF, Faccenda E, Harding SD, Davies JA et al. (2023) The Concise Guide to PHARMACOLOGY 2023/24: Enzymes. Br J Pharmacol. 180 Suppl 2:S289-373.