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CYP2 family: physiological enzymes subset C


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Compared to the other CYP2 family enzymes, this subset have physiological rather than drug metabolising enzyme activities.


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CYP2R1 C Show summary »

CYP2S1 C Show summary »

CYP2U1 C Show summary »

Target Id 1335
Nomenclature CYP2U1
Previous and unofficial names cytochrome P450 2U1 | cytochrome P450, family 2, subfamily u, polypeptide 1 | cytochrome P450, family 2, subfamily U, polypeptide 1 | cytochrome P450
Genes CYP2U1 (Hs), Cyp2u1 (Mm), Cyp2u1 (Rn)
Ensembl ID ENSG00000155016 (Hs), ENSMUSG00000027983 (Mm), ENSRNOG00000011053 (Rn)
UniProtKB AC Q7Z449 (Hs), Q9CX98 (Mm), Q4V8D1 (Rn)
EC number
Comment Thymus and brain specific catalysis of ω- and (ω-1)-hydroxylation of fatty acids [2]. Oxidation of N-arachidonoylserotonin [7]. Mutations have been associated with hereditary spastic paraplegia [4].

CYP2W1 C Show summary »


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NC-IUPHAR subcommittee and family contributors

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How to cite this family page

Database page citation (select format):

Concise Guide to PHARMACOLOGY citation:

Alexander SPH, Fabbro D, Kelly E, Mathie AA, Peters JA, Veale EL, Armstrong JF, Faccenda E, Harding SD, Davies JA et al. (2023) The Concise Guide to PHARMACOLOGY 2023/24: Enzymes. Br J Pharmacol. 180 Suppl 2:S289-373.