Top ▲ Aldehyde oxidase

Unless otherwise stated all data on this page refer to the human proteins. Gene information is provided for human (Hs), mouse (Mm) and rat (Rn).


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aldehyde oxidase 1 Show summary »

Target Id 3186
Nomenclature aldehyde oxidase 1
Genes AOX1 (Hs), Aox1 (Mm), Aox1 (Rn)
Ensembl ID ENSG00000138356 (Hs), ENSMUSG00000063558 (Mm), ENSRNOG00000015354 (Rn)
UniProtKB AC Q06278 (Hs), O54754 (Mm)
Comment Aldehyde oxidase 1 is a cytosolic enzyme that catalyses the oxidation of aldehydes into carboxylic acid and hydrogen peroxide. It is an important hepatic drug-metabolising enzyme [2-3], and its involvement in free-radical generation has implicated its activity in disease pathology [1,4].


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How to cite this family page

Database page citation: Aldehyde oxidase. Accessed on 02/03/2024. IUPHAR/BPS Guide to PHARMACOLOGY,

Concise Guide to PHARMACOLOGY citation:

Alexander SPH, Fabbro D, Kelly E, Mathie AA, Peters JA, Veale EL, Armstrong JF, Faccenda E, Harding SD, Davies JA et al. (2023) The Concise Guide to PHARMACOLOGY 2023/24: Enzymes. Br J Pharmacol. 180 Suppl 2:S289-373.