Top ▲

1.2.3.1 Aldehyde oxidase

Unless otherwise stated all data on this page refer to the human proteins. Gene information is provided for human (Hs), mouse (Mm) and rat (Rn).

Enzymes

3186
Click here for help

aldehyde oxidase 1 Show summary »


Target Id 3186
Nomenclature aldehyde oxidase 1
Genes AOX1 (Hs), Aox1 (Mm), Aox1 (Rn)
Ensembl ID ENSG00000138356 (Hs), ENSMUSG00000063558 (Mm), ENSRNOG00000015354 (Rn)
UniProtKB AC Q06278 (Hs), O54754 (Mm)
Comment Aldehyde oxidase 1 is a cytosolic enzyme that catalyses the oxidation of aldehydes into carboxylic acid and hydrogen peroxide. It is an important hepatic drug-metabolising enzyme [2-3], and its involvement in free-radical generation has implicated its activity in disease pathology [1,4].

References

Click here for help

Show »

How to cite this family page

Database page citation:

1.2.3.1 Aldehyde oxidase. Accessed on 02/03/2024. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/FamilyDisplayForward?familyId=1068.

Concise Guide to PHARMACOLOGY citation:

Alexander SPH, Fabbro D, Kelly E, Mathie AA, Peters JA, Veale EL, Armstrong JF, Faccenda E, Harding SD, Davies JA et al. (2023) The Concise Guide to PHARMACOLOGY 2023/24: Enzymes. Br J Pharmacol. 180 Suppl 2:S289-373.