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Autophagy receptors

Unless otherwise stated all data on this page refer to the human proteins. Gene information is provided for human (Hs), mouse (Mm) and rat (Rn).


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Autophagy receptors are important for protein homeostasis, by regulating the clearance of protein aggregates, pathogens and the turnover of a wide range of cargo proteins, via the autophagosome-lysosome pathway, by ubiquitin-dependent and -independent mechanisms [3]. Their activity is modulated by protein modifications such as phosphorylation and ubiquitination. Some autophagy receptors have been associated with neurodegenerative diseases [2,10].


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How to cite this family page

Database page citation:

Autophagy receptors. Accessed on 30/11/2023. IUPHAR/BPS Guide to PHARMACOLOGY,

Concise Guide to PHARMACOLOGY citation:

Alexander SP, Kelly E, Mathie A, Peters JA, Veale EL et al. (2021) THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: Introduction and Other Protein Targets. Br J Pharmacol. 178 Suppl 1:S1-S26.