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E2 ubiquitin-conjugating enzymes

Unless otherwise stated all data on this page refer to the human proteins. Gene information is provided for human (Hs), mouse (Mm) and rat (Rn).

Enzymes

3229
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ubiquitin conjugating enzyme E2 D1 Show summary »

ubiquitin conjugating enzyme E2 D2 Show summary »


Target Id 3229
Nomenclature ubiquitin conjugating enzyme E2 D2
Genes UBE2D2 (Hs), Ube2d2a (Mm), Ube2d2 (Rn)
Ensembl ID ENSG00000131508 (Hs), ENSMUSG00000091896 (Mm), ENSRNOG00000069286 (Rn)
UniProtKB AC P62837 (Hs), P51669 (Mm), P62838 (Mm), P62839 (Rn)
EC number
2.3.2.23
2.3.2.24
Comment One of four human UBE2D genes (UBE2D1-4), that encode E2 ubiquitin-conjugating enzymes, that are involved in the second step in the ubiquitination process that ultimately leads to proteosome-mediated protein degradation.

References

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How to cite this family page

Database page citation:

E2 ubiquitin-conjugating enzymes. Accessed on 29/02/2024. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/FamilyDisplayForward?familyId=1078.

Concise Guide to PHARMACOLOGY citation:

Alexander SPH, Fabbro D, Kelly E, Mathie AA, Peters JA, Veale EL, Armstrong JF, Faccenda E, Harding SD, Davies JA et al. (2023) The Concise Guide to PHARMACOLOGY 2023/24: Enzymes. Br J Pharmacol. 180 Suppl 2:S289-373.