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Unless otherwise stated all data on this page refer to the human proteins. Gene information is provided for human (Hs), mouse (Mm) and rat (Rn).


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Selenoenzymes are a family of catalytic proteins that contain at least one selenocysteine (Se-Cys) amino acid residue. In humans several selenoenzymes have been identified, including glutathione peroxidases (GPX), thioredoxin reductases (TrxR/TXNRD) and iodothyronine deiodinases (DIO).


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glutathione peroxidase 4 Show summary »


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How to cite this family page

Database page citation:

Selenoenzymes. Accessed on 28/09/2023. IUPHAR/BPS Guide to PHARMACOLOGY,

Concise Guide to PHARMACOLOGY citation:

Alexander SP, Fabbro D, Kelly E, Mathie A, Peters JA, Veale EL et al. (2021) THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: Enzymes. Br J Pharmacol. 178 Suppl 1:S313-S411.