V-type ATPase | Transporters | IUPHAR/BPS Guide to PHARMACOLOGY

V-type ATPase C

Unless otherwise stated all data on this page refer to the human proteins. Gene information is provided for human (Hs), mouse (Mm) and rat (Rn).

Overview

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The V-type ATPase is most prominently associated with lysosomes in mammals, but also appears to be expressed on the plasma membrane and neuronal synaptic vesicles.

The V₁ motor, responsible for ATP turnover, has eight subunits with a composition of A-H.

The V₀ motor, responsible for ion translocation, has six subunits (a-e).

Transporters

Complexes

V-type ATPase V₁ motor Show summary »« Hide summary

V-type ATPase V₀ motor Show summary »« Hide summary

Transporters and Subunits

V-type ATPase V₁ motor A subunit Show summary »« Hide summary

Target Id	810
Nomenclature	V-type ATPase V₁ motor A subunit
Previous and unofficial names	ATPase, H+ transporting, lysosomal V1 subunit A \| V-type proton ATPase catalytic subunit A \| ATP6A1 \| ATP6V1A1 \| VA68 \| Vma1 \| VPP2 \| ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A \| ATPase, H transporting, lysosomal V1 subunit A \| ATPase
Complexes	V-type ATPase V₁ motor
Genes	ATP6V1A (Hs), Atp6v1a (Mm), Atp6v1a (Rn)
Ensembl ID	ENSG00000114573 (Hs), ENSMUSG00000052459 (Mm), ENSRNOG00000001992 (Rn)
UniProtKB AC	P38606 (Hs), P50516 (Mm)

V-type ATPase V₁ motor B1 subunit Show summary »« Hide summary

Target Id	811
Nomenclature	V-type ATPase V₁ motor B1 subunit
Previous and unofficial names	Renal tubular acidosis with deafness \| vacuolar proton pump 3 \| ATPase, H transporting, lysosomal V1 subunit B1 \| ATPase, H+ transporting, V1 subunit B, isoform 1 \| V-type proton ATPase subunit B, kidney isoform \| ATP6B1 \| RTA1B \| VATB \| Vma2 \| VPP3 \| ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B1 \| ATPase, H+ transporting, lysosomal V1 subunit B1 \| ATPase
Complexes	V-type ATPase V₁ motor
Genes	ATP6V1B1 (Hs), Atp6v1b1 (Mm), Atp6v1b1 (Rn)
Ensembl ID	ENSG00000116039 (Hs), ENSMUSG00000006269 (Mm), ENSRNOG00000013573 (Rn)
UniProtKB AC	P15313 (Hs)

V-type ATPase V₁ motor B2 subunit Show summary »« Hide summary

Target Id

812

Nomenclature

V-type ATPase V₁ motor B2 subunit

Previous and unofficial names

Complexes

V-type ATPase V₁ motor

Genes

ATP6V1B2 (Hs), Atp6v1b2 (Mm), Atp6v1b2 (Rn)

Ensembl ID

ENSG00000147416 (Hs), ENSMUSG00000006273 (Mm), ENSRNOG00000011891 (Rn)

UniProtKB AC

P21281 (Hs), P62814 (Mm), P62815 (Rn)

Inhibitors

enoxacin pIC₅₀ 5.0 [1]

V-type ATPase V₁ motor C1 subunit Show summary »« Hide summary

Target Id	813
Nomenclature	V-type ATPase V₁ motor C1 subunit
Previous and unofficial names	vacuolar proton pump subunit C 1 \| ATPase, H+ transporting, lysosomal V1 subunit C1 \| V-ATPase subunit C 1 \| V-type proton ATPase subunit C 1 \| ATP6C \| ATP6D \| ATPase, H+ transporting, lysosomal (vacuolar proton pump) 42kD \| ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C, isoform 1 \| VATC \| Vma5 \| ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1 \| ATPase, H transporting, lysosomal V1 subunit C1 \| ATPase
Complexes	V-type ATPase V₁ motor
Genes	ATP6V1C1 (Hs), Atp6v1c1 (Mm), Atp6v1c1 (Rn)
Ensembl ID	ENSG00000155097 (Hs), ENSMUSG00000022295 (Mm), ENSRNOG00000004846 (Rn)
UniProtKB AC	P21283 (Hs), Q9Z1G3 (Mm), Q5FVI6 (Rn)

V-type ATPase V₁ motor C2 subunit Show summary »« Hide summary

Target Id	814
Nomenclature	V-type ATPase V₁ motor C2 subunit
Previous and unofficial names	vacuolar H+ ATPase C2 \| vacuolar proton pump subunit C 2 \| V-ATPase subunit C 2 \| V-type ATPase C2 subunit a isoform \| V-type proton ATPase subunit C 2 \| ATP6C2 \| ATPase, H+ transporting, lysosomal 42kD, V1 subunit C isoform 2 \| ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C isoform 2 \| VMA5 \| ATPase, H+ transporting, lysosomal V1 subunit C2 \| ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C2 \| ATPase, H transporting, lysosomal V1 subunit C2 \| ATPase
Complexes	V-type ATPase V₁ motor
Genes	ATP6V1C2 (Hs), Atp6v1c2 (Mm), Atp6v1c2 (Rn)
Ensembl ID	ENSG00000143882 (Hs), ENSMUSG00000020566 (Mm), ENSRNOG00000050553 (Rn)
UniProtKB AC	Q8NEY4 (Hs), Q99L60 (Mm), Q6AYE4 (Rn)

V-type ATPase V₁ motor D subunit Show summary »« Hide summary

Target Id	815
Nomenclature	V-type ATPase V₁ motor D subunit
Previous and unofficial names	ATP6M \| ATPase, H+ transporting, lysosomal (vacuolar proton pump) \| ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D \| VATD \| VMA8 \| V-type proton ATPase subunit D \| ATPase, H transporting, lysosomal V1 subunit D \| ATPase
Complexes	V-type ATPase V₁ motor
Genes	ATP6V1D (Hs), Atp6v1d (Mm), Atp6v1d (Rn)
Ensembl ID	ENSG00000100554 (Hs), ENSMUSG00000021114 (Mm), ENSRNOG00000009080 (Rn)
UniProtKB AC	Q9Y5K8 (Hs), P57746 (Mm)

V-type ATPase V₁ motor E1 subunit Show summary »« Hide summary

Target Id	816
Nomenclature	V-type ATPase V₁ motor E1 subunit
Previous and unofficial names	ATP6E \| ATP6E2 \| ATP6V1E \| ATPase, H+ transporting, lysosomal (vacuolar proton pump) 31kD \| ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E \| ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E isoform 1 \| E2 \| H(+)-ATPase E-like protein \| H+ ATPase subunit E \| P31 \| vacuolar H(+)-ATPase, E subunit \| vacuolar H+ ATPase E1 \| vacuolar proton pump subunit E 1 \| V-ATPase subunit E 1 \| VATPase, H+ transporting, lysosomal V1 subunit E1 \| Vma4 \| V-type proton ATPase subunit E 1 \| ATPase, H+ transporting, lysosomal V1 subunit E1 \| ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E1 \| ATPase, H transporting, lysosomal V1 subunit E1 \| ATPase
Complexes	V-type ATPase V₁ motor
Genes	ATP6V1E1 (Hs), Atp6v1e1 (Mm), Atp6v1e1 (Rn)
Ensembl ID	ENSG00000131100 (Hs), ENSMUSG00000019210 (Mm), ENSRNOG00000011905 (Rn)
UniProtKB AC	P36543 (Hs), P50518 (Mm), Q6PCU2 (Rn)

V-type ATPase V₁ motor E2 subunit Show summary »« Hide summary

Target Id	817
Nomenclature	V-type ATPase V₁ motor E2 subunit
Previous and unofficial names	ATP6E1 \| ATP6EL2 \| ATP6V1EL2 \| ATPase, H transporting, lysosomal V1 subunit E2 \| ATPase, H+ transporting, lysosomal (vacuolar proton pump) 31kD-like 2 \| ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E isoform 2 \| ATPase, H+ transporting, V1 subunit E-like 2 \| E1 \| VMA4 \| V-type proton ATPase subunit E 2 \| ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E2 \| ATPase, H+ transporting, lysosomal V1 subunit E2 \| ATPase
Complexes	V-type ATPase V₁ motor
Genes	ATP6V1E2 (Hs), Atp6v1e2 (Mm), Atp6v1e2 (Rn)
Ensembl ID	ENSG00000250565 (Hs), ENSMUSG00000053375 (Mm), ENSRNOG00000015566 (Rn)
UniProtKB AC	Q96A05 (Hs), Q9D593 (Mm)

V-type ATPase V₁ motor F subunit Show summary »« Hide summary

Target Id	818
Nomenclature	V-type ATPase V₁ motor F subunit
Previous and unofficial names	ATP6S14 \| ATPase, H transporting, lysosomal V1 subunit F \| ATPase, H+ transporting, V1 subunit F \| ATPase, vacuolar, 14 kD \| vacuolar proton pump subunit F \| VATF \| V-ATPase 14 kDa subunit \| V-ATPase subunit F \| Vma7 \| V-type proton ATPase subunit F \| ATPase, H+ transporting, lysosomal V1, subunit F \| ATPase, H+ transporting, lysosomal 14kDa, V1 subunit F \| ATPase, H transporting, lysosomal V1, subunit F \| ATPase \| ATPase, H+ transporting, lysosomal V1 subunit F
Complexes	V-type ATPase V₁ motor
Genes	ATP6V1F (Hs), Atp6v1f (Mm), Atp6v1f (Rn)
Ensembl ID	ENSG00000128524 (Hs), ENSMUSG00000004285 (Mm), ENSRNOG00000007392 (Rn)
UniProtKB AC	Q16864 (Hs), Q9D1K2 (Mm), P50408 (Rn)

V-type ATPase V₁ motor G1 subunit Show summary »« Hide summary

Target Id	819
Nomenclature	V-type ATPase V₁ motor G1 subunit
Previous and unofficial names	ATP6G \| ATP6G1 \| ATP6GL \| ATP6J \| ATPase, H transporting, lysosomal V1 subunit G1 \| ATPase, H+ transporting, lysosomal (vacuolar proton pump), member J \| ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G isoform 1 \| VAG1 \| Vma10 \| V-type proton ATPase subunit G 1 \| ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G1 \| ATPase, H+ transporting, lysosomal V1 subunit G1 \| ATPase
Complexes	V-type ATPase V₁ motor
Genes	ATP6V1G1 (Hs), Atp6v1g1 (Mm), Atp6v1g1 (Rn)
Ensembl ID	ENSG00000136888 (Hs), ENSMUSG00000039105 (Mm), ENSRNOG00000063197 (Rn)
UniProtKB AC	O75348 (Hs), Q9CR51 (Mm)

V-type ATPase V₁ motor G2 subunit Show summary »« Hide summary

Target Id	820
Nomenclature	V-type ATPase V₁ motor G2 subunit
Previous and unofficial names	ATP6G \| ATP6G2 \| ATPase, H+ transporting, lysosomal (vacuolar proton pump) \| ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G isoform 2 \| NG38 \| vacuolar ATPase NG38 \| VAG2 \| Vma10 \| V-type proton ATPase subunit G 2 \| ATPase, H+ transporting, lysosomal V1 subunit G2 \| ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2 \| ATPase, H transporting, lysosomal V1 subunit G2 \| ATPase
Complexes	V-type ATPase V₁ motor
Genes	ATP6V1G2 (Hs), Atp6v1g2 (Mm), Atp6v1g2 (Rn)
Ensembl ID	ENSG00000213760 (Hs), ENSMUSG00000024403 (Mm), ENSRNOG00000000840 (Rn)
UniProtKB AC	O95670 (Hs), Q9WTT4 (Mm)

V-type ATPase V₁ motor G3 subunit Show summary »« Hide summary

Target Id	821
Nomenclature	V-type ATPase V₁ motor G3 subunit
Previous and unofficial names	ATP6G3 \| ATPase, H transporting, lysosomal V1 subunit G3 \| ATPase, H+ transporting, lysosomal 13kD, V1 subunit G isoform 3 \| ATPase, H+ transporting, lysosomal V1 subunit G3 \| Vma10 \| V-type proton ATPase subunit G 3 \| ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G3 \| ATPase, H transporting, lysosomal V1 subunit G3 \| ATPase
Complexes	V-type ATPase V₁ motor
Genes	ATP6V1G3 (Hs), Atp6v1g3 (Mm), Atp6v1g3 (Rn)
Ensembl ID	ENSG00000151418 (Hs), ENSMUSG00000026394 (Mm), ENSRNOG00000022480 (Rn)
UniProtKB AC	Q96LB4 (Hs), Q8BMC1 (Mm)

V-type ATPase V₁ motor H subunit Show summary »« Hide summary

Target Id	822
Nomenclature	V-type ATPase V₁ motor H subunit
Previous and unofficial names	CGI-11 \| ATPase, H+ transporting, lysosomal 50/57kD, V1 subunit H \| ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H \| SFD \| SFDalpha \| SFDbeta \| vacuolar ATP synthase subunit H \| vacuolar ATPase subunit H \| vacuolar proton pump H subunit \| V-ATPase H subunit \| VMA13 \| V-type proton ATPase subunit H \| ATPase, H transporting, lysosomal V1 subunit H \| ATPase
Complexes	V-type ATPase V₁ motor
Genes	ATP6V1H (Hs), Atp6v1h (Mm), Atp6v1h (Rn)
Ensembl ID	ENSG00000047249 (Hs), ENSMUSG00000033793 (Mm), ENSRNOG00000030862 (Rn)
UniProtKB AC	Q9UI12 (Hs), Q8BVE3 (Mm)

V-type ATPase V₀ motor a1 subunit Show summary »« Hide summary

Target Id	823
Nomenclature	V-type ATPase V₀ motor a1 subunit
Previous and unofficial names	a1 \| V-ATPase 116 kDa \| vacuolar adenosine triphosphatase subunit Ac116 \| ATP6N1 \| ATP6N1A \| ATPase H+ transporting lysosomal (vacuolar proton pump) noncatalytic accessory protein 1 (110/160 kDa) \| ATPase, H+ transporting, lysosomal noncatalytic accessory protein 1a \| ATPase, H+ transporting, lysosomal (vacuolar proton pump) non-catalytic accessory protein 1A (110/116kD) \| ATPase, H+ transporting, lysosomal V0 subunit a \| ATPase, H+ transporting, lysosomal V0 subunit a isoform 1 \| ATPase, H+ transporting, lysosomal V0 subunit A1 \| clathrin-coated vesicle/synaptic vesicle proton pump 116 kDa subunit \| Stv1 \| vacuolar proton pump subunit 1 \| vacuolar proton translocating ATPase 116 kDa subunit a \| V-ATPase a1 \| v-H+ATPase subunit a1 \| Vph1 \| VPP1 \| V-type proton ATPase 116 kDa subunit a \| V-type proton ATPase 116 kDa subunit a isoform 1 \| ATPase, H+ transporting, lysosomal V0 subunit a1 \| ATPase, H transporting, lysosomal V0 subunit A1 \| ATPase
Complexes	V-type ATPase V₀ motor
Genes	ATP6V0A1 (Hs), Atp6v0a1 (Mm), Atp6v0a1 (Rn)
Ensembl ID	ENSG00000033627 (Hs), ENSMUSG00000019302 (Mm), ENSRNOG00000036814 (Rn)
UniProtKB AC	Q93050 (Hs), Q9Z1G4 (Mm), P25286 (Rn)

V-type ATPase V₀ motor a2 subunit Show summary »« Hide summary

Target Id	824
Nomenclature	V-type ATPase V₀ motor a2 subunit
Previous and unofficial names	a2 \| ATPase, H+ transporting, lysosomal V0 subunit a isoform 2 \| ATPase, H+ transporting, lysosomal V0 subunit A2 \| ATP6a2 \| ATP6N1D \| Atp6n2 \| Cc1-3 \| infantile malignant osteopetrosis \| J6B7 \| Stv1 \| TJ6 \| TJ6M \| TJ6s \| V-ATPase a2 \| Vph1 \| V-type proton ATPase 116 kDa subunit a isoform 2 \| ATPase, H+ transporting, lysosomal V0 subunit a2 \| ATPase, H transporting, lysosomal V0 subunit A2 \| ATPase
Complexes	V-type ATPase V₀ motor
Genes	ATP6V0A2 (Hs), Atp6v0a2 (Mm), Atp6v0a2 (Rn)
Ensembl ID	ENSG00000185344 (Hs), ENSMUSG00000038023 (Mm), ENSRNOG00000052704 (Rn)
UniProtKB AC	Q9Y487 (Hs), P15920 (Mm)

V-type ATPase V₀ motor a3 subunit Show summary »« Hide summary

Target Id	825
Nomenclature	V-type ATPase V₀ motor a3 subunit
Previous and unofficial names	Atp6i \| ATP6N1C \| ATP6V0A3 \| OC116 \| TIRC7 \| a3 \| T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 protein A3 \| ATPase, H+ transporting, lysosomal V0 protein a \| osteoclastic proton pump \| T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 protein a \| v-ATPase 116-kDa \| v-H+ATPase subunit a3 \| V-type proton ATPase 116 kDa subunit a \| V-type proton ATPase 116 kDa subunit a isoform 3 \| V-ATPase a3 \| ATP6a3 \| T-cell, immune regulator 1, ATPase, H transporting, lysosomal V0 subunit A3 \| T-cell immune regulator 1, ATPase H+ transporting V0 subunit A3 \| T cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 protein A3 \| T-cell immune regulator 1, ATPase H+ transporting V0 subunit a3 \| T cell
Complexes	V-type ATPase V₀ motor
Genes	TCIRG1 (Hs), Tcirg1 (Mm), Tcirg1 (Rn)
Ensembl ID	ENSG00000110719 (Hs), ENSMUSG00000001750 (Mm), ENSRNOG00000017220 (Rn)
UniProtKB AC	Q13488 (Hs)

V-type ATPase V₀ motor a4 subunit Show summary »« Hide summary

Target Id	826
Nomenclature	V-type ATPase V₀ motor a4 subunit
Previous and unofficial names	ATP6N1B \| ATP6N2 \| RDRTA2 \| RTA1C \| RTADR \| Stv1 \| Vph1 \| VPP2 \| ATPase, H+ transporting, lysosomal (vacuolar proton pump) non-catalytic accessory protein 1B \| ATPase, H+ transporting, lysosomal V0 subunit a isoform 4 \| ATPase, H+ transporting, lysosomal V0 subunit A4 \| ATPase, H+ transporting, lysosomal V0 subunit A \| V-type proton ATPase 116 kDa subunit a \| V-type proton ATPase 116 kDa subunit a isoform 4 \| V-ATPase alpha 4 \| ATPase, H+ transporting, lysosomal V0 subunit a4 \| ATPase, H transporting, lysosomal V0 subunit A4 \| ATPase
Complexes	V-type ATPase V₀ motor
Genes	ATP6V0A4 (Hs), Atp6v0a4 (Mm), Atp6v0a4 (Rn)
Ensembl ID	ENSG00000105929 (Hs), ENSMUSG00000038600 (Mm), ENSRNOG00000013428 (Rn)
UniProtKB AC	Q9HBG4 (Hs), Q920R6 (Mm)

V-type ATPase V₀ motor b subunit Show summary »« Hide summary

Target Id	827
Nomenclature	V-type ATPase V₀ motor b subunit
Previous and unofficial names	ATP6F \| HATPL \| VMA16 \| ATPase, H+ transporting, lysosomal (vacuolar proton pump) 21kD \| ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b \| ATPase, H+ transporting, V0 subunit B \| V-type proton ATPase 21 kDa proteolipid subunit \| ATPase, H+ transporting, lysosomal V0 subunit B \| ATPase, H transporting, lysosomal V0 subunit B \| ATPase
Complexes	V-type ATPase V₀ motor
Genes	ATP6V0B (Hs), Atp6v0b (Mm), Atp6v0b (Rn)
Ensembl ID	ENSG00000117410 (Hs), ENSMUSG00000033379 (Mm), ENSRNOG00000019655 (Rn)
UniProtKB AC	Q99437 (Hs), Q91V37 (Mm)

V-type ATPase V₀ motor c subunit Show summary »« Hide summary

Target Id	828
Nomenclature	V-type ATPase V₀ motor c subunit
Previous and unofficial names	ATP6C \| ATP6L \| ATPL \| VATL \| Vma3 \| ATPase, H+ transporting, lysosomal (vacuolar proton pump) 16 kDa \| ATPase, H+ transporting, lysosomal (vacuolar proton pump), subunit C \| ATPase, H+ transporting, lysosomal 1 \| ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c \| vacuolar proton pump 16 kDa proteolipid subunit \| V-ATPase 16 kDa proteolipid subunit \| V-type proton ATPase 16 kDa proteolipid subunit \| Atp6c2 \| Atpl-rs1 \| H(+)-ATPase (mvp) \| PL16 \| proteolipid \| ATPase, H+ transporting, lysosomal V0 subunit C \| ATPase, H transporting, lysosomal V0 subunit C \| ATPase
Complexes	V-type ATPase V₀ motor
Genes	ATP6V0C (Hs), Atp6v0c (Mm), Atp6v0c (Rn)
Ensembl ID	ENSG00000185883 (Hs), ENSMUSG00000024121 (Mm), ENSRNOG00000006542 (Rn)
UniProtKB AC	P27449 (Hs), P63082 (Mm), P63081 (Rn)

V-type ATPase V₀ motor d1 subunit Show summary »« Hide summary

Target Id	829
Nomenclature	V-type ATPase V₀ motor d1 subunit
Previous and unofficial names	ATP6D \| ATP6DV \| P39 \| VATX \| Vma6 \| VPATPD \| ATPase, H+ transporting, lysosomal (vacuolar proton pump), member D \| ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d isoform 1 \| ATPase, H+ transporting, lysosomal 38kDa, V0 subunit D1 \| ATPase, H+ transporting, V0 subunit D \| ATPase, H+ transporting, V0 subunit D isoform 1 \| V-type proton ATPase subunit d 1 \| Ac39 \| ATPase, H+ transporting, lysosomal V0 subunit D1 \| ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1 \| ATPase, H transporting, lysosomal V0 subunit D1 \| ATPase
Complexes	V-type ATPase V₀ motor
Genes	ATP6V0D1 (Hs), Atp6v0d1 (Mm), Atp6v0d1 (Rn)
Ensembl ID	ENSG00000159720 (Hs), ENSMUSG00000013160 (Mm), ENSRNOG00000017235 (Rn)
UniProtKB AC	P61421 (Hs), P51863 (Mm)

V-type ATPase V₀ motor d2 subunit Show summary »« Hide summary

Target Id	830
Nomenclature	V-type ATPase V₀ motor d2 subunit
Previous and unofficial names	ATP6D2 \| VMA6 \| ATPase, H+ transporting, lysosomal 38kD, V0 subunit d isoform 2 \| ATPase, H+ transporting, lysosomal 38kDa, V0 subunit D2 \| ATPase, H+ transporting, V0 subunit D, isoform 2 \| vacuolar proton pump subunit d 2 \| V-ATPase subunit d 2 \| V-type proton ATPase subunit d 2 \| ATPase, H+ transporting, lysosomal V0 subunit D2 \| ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d2 \| ATPase, H transporting, lysosomal V0 subunit D2 \| ATPase
Complexes	V-type ATPase V₀ motor
Genes	ATP6V0D2 (Hs), Atp6v0d2 (Mm), Atp6v0d2 (Rn)
Ensembl ID	ENSG00000147614 (Hs), ENSMUSG00000028238 (Mm), ENSRNOG00000006926 (Rn)
UniProtKB AC	Q8N8Y2 (Hs), Q80SY3 (Mm), Q5FVL0 (Rn)

V-type ATPase V₀ motor e1 subunit Show summary »« Hide summary

Target Id	831
Nomenclature	V-type ATPase V₀ motor e1 subunit
Previous and unofficial names	ATP6H \| ATP6V0E \| ATPase, H+ transporting, lysosomal (vacuolar proton pump) 9kD \| ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e \| Atp6k \| ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1 \| ATPase, H+ transporting, lysosomal V0 subunit E1 \| ATPase, H+ transporting, V0 subunit E isoform 1 \| D-serine-regulated transcript 1 protein \| dsr-1 \| Dsr-1A \| vacuolar proton pump subunit e 1 \| vacuolar proton-ATPase subunit M9.2 \| V-ATPase 9.2 kDa membrane accessory protein \| V-ATPase M9.2 subunit \| V-ATPase subunit e 1 \| V-type proton ATPase subunit e 1 \| lysosomal 9kDa \| ATPase, H+ transporting, lysosomal, V0 subunit e1 \| ATPase, H transporting, lysosomal, V0 subunit e1 \| ATPase \| ATPase, H+ transporting, lysosomal V0 subunit E
Complexes	V-type ATPase V₀ motor
Genes	ATP6V0E1 (Hs), Atp6v0e (Mm), Atp6v0e1 (Rn)
Ensembl ID	ENSG00000113732 (Hs), ENSMUSG00000015575 (Mm), ENSRNOG00000003269 (Rn)
UniProtKB AC	O15342 (Hs), Q9CQD8 (Mm), Q794C0 (Rn)

V-type ATPase V₀ motor e2 subunit Show summary »« Hide summary

Target Id	832
Nomenclature	V-type ATPase V₀ motor e2 subunit
Previous and unofficial names	ATP6V0E2L \| ATPase, H+ transporting, lysosomal V0 subunit E2 \| ATPase, H+ transporting, V0 subunit E \| ATPase, H+ transporting, V0 subunit E isoform 2 \| NM9.2 \| vacuolar proton pump subunit e 2 \| V-ATPase subunit e 2 \| V-type proton ATPase subunit e 2 \| ATPase, H+ transporting V0 subunit e2 \| ATPase, H transporting V0 subunit e2 \| ATPase
Complexes	V-type ATPase V₀ motor
Genes	ATP6V0E2 (Hs), Atp6v0e2 (Mm), Atp6v0e2 (Rn)
Ensembl ID	ENSG00000171130 (Hs), ENSMUSG00000039347 (Mm), ENSRNOG00000008218 (Rn)
UniProtKB AC	Q8NHE4 (Hs), Q91XE7 (Mm), Q5EB76 (Rn)

References

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How to cite this family page

Database page citation:

V-type ATPase. Accessed on 12/09/2024. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/FamilyDisplayForward?familyId=157.

Concise Guide to PHARMACOLOGY citation:

Alexander SPH, Fabbro D, Kelly E, Mathie AA, Peters JA, Veale EL, Armstrong JF, Faccenda E, Harding SD, Davies JA et al. (2023) The Concise Guide to PHARMACOLOGY 2023/24: Transporters. Br J Pharmacol. 180 Suppl 2:S374-469.

V-type ATPase C

Overview

Transporters

Complexes

Transporters and Subunits

Further reading

References

How to cite this family page