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V-type ATPase C

Unless otherwise stated all data on this page refer to the human proteins. Gene information is provided for human (Hs), mouse (Mm) and rat (Rn).

Overview

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The V-type ATPase is most prominently associated with lysosomes in mammals, but also appears to be expressed on the plasma membrane and neuronal synaptic vesicles.

The V1 motor, responsible for ATP turnover, has eight subunits with a composition of A-H.

The V0 motor, responsible for ion translocation, has six subunits (a-e).

Transporters

823
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Complexes

V-type ATPase V1 motor Show summary »

V-type ATPase V0 motor Show summary »

Transporters and Subunits

V-type ATPase V1 motor A subunit Show summary »

V-type ATPase V1 motor B1 subunit Show summary »

V-type ATPase V1 motor B2 subunit Show summary »

V-type ATPase V1 motor C1 subunit Show summary »

V-type ATPase V1 motor C2 subunit Show summary »

V-type ATPase V1 motor D subunit Show summary »

V-type ATPase V1 motor E1 subunit Show summary »

V-type ATPase V1 motor E2 subunit Show summary »

V-type ATPase V1 motor F subunit Show summary »

V-type ATPase V1 motor G1 subunit Show summary »

V-type ATPase V1 motor G2 subunit Show summary »

V-type ATPase V1 motor G3 subunit Show summary »

V-type ATPase V1 motor H subunit Show summary »

V-type ATPase V0 motor a1 subunit Show summary »


Target Id 823
Nomenclature V-type ATPase V0 motor a1 subunit
Previous and unofficial names a1 | V-ATPase 116 kDa | V-ATPase a1 | ATP6N1 | ATP6N1A | ATPase H+ transporting lysosomal (vacuolar proton pump) noncatalytic accessory protein 1 (110/160 kDa) | ATPase, H+ transporting, lysosomal noncatalytic accessory protein 1a | ATPase, H+ transporting, lysosomal (vacuolar proton pump) non-catalytic accessory protein 1A (110/116kD) | ATPase, H+ transporting, lysosomal V0 subunit a | ATPase, H+ transporting, lysosomal V0 subunit a isoform 1 | ATPase, H+ transporting, lysosomal V0 subunit A1 | clathrin-coated vesicle/synaptic vesicle proton pump 116 kDa subunit | Stv1 | vacuolar adenosine triphosphatase subunit Ac116 | vacuolar proton pump subunit 1 | vacuolar proton translocating ATPase 116 kDa subunit a | v-H+ATPase subunit a1 | Vph1 | VPP1 | V-type proton ATPase 116 kDa subunit a | V-type proton ATPase 116 kDa subunit a isoform 1 | ATPase, H+ transporting, lysosomal V0 subunit a1 | ATPase, H transporting, lysosomal V0 subunit A1 | ATPase
Complexes V-type ATPase V0 motor
Genes ATP6V0A1 (Hs), Atp6v0a1 (Mm), Atp6v0a1 (Rn)
Ensembl ID ENSG00000033627 (Hs), ENSMUSG00000019302 (Mm), ENSRNOG00000036814 (Rn)
UniProtKB AC Q93050 (Hs), Q9Z1G4 (Mm), P25286 (Rn)

V-type ATPase V0 motor a2 subunit Show summary »

V-type ATPase V0 motor a3 subunit Show summary »

V-type ATPase V0 motor a4 subunit Show summary »

V-type ATPase V0 motor b subunit Show summary »

V-type ATPase V0 motor c subunit Show summary »

V-type ATPase V0 motor d1 subunit Show summary »

V-type ATPase V0 motor d2 subunit Show summary »

V-type ATPase V0 motor e1 subunit Show summary »

V-type ATPase V0 motor e2 subunit Show summary »

Further reading

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References

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How to cite this family page

Database page citation:

V-type ATPase. Accessed on 24/10/2021. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/FamilyDisplayForward?familyId=157.

Concise Guide to PHARMACOLOGY citation:

Alexander SPH, Kelly E, Mathie A, Peters JA, Veale EL, Armstrong JF, Faccenda E, Harding SD, Pawson AJ, Sharman JL, Southan C, Davies JA; CGTP Collaborators. (2019) The Concise Guide to PHARMACOLOGY 2019/20: Transporters. Br J Pharmacol. 176 Issue S1: S397-S493.