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SLC7 family C

Unless otherwise stated all data on this page refer to the human proteins. Gene information is provided for human (Hs), mouse (Mm) and rat (Rn).


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SLC7 family members may be divided into two major groups: cationic amino acid transporters (CATs) and glycoprotein-associated amino acid transporters (gpaATs).

Cationic amino acid transporters are 14 TM proteins, which mediate pH- and sodium-independent transport of cationic amino acids (system y+), apparently as an exchange mechanism. These transporters are sensitive to inhibition by N-ethylmaleimide.


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CAT1 (High affinity cationic amino acid transporter 1 / SLC7A1) C Show summary »

CAT2 (Low affinity cationic amino acid transporter 2 / SLC7A2) C Show summary »

CAT3 (Cationic amino acid transporter 3 / SLC7A3) C Show summary »

CAT4 (Cationic amino acid transporter 4 / SLC7A4) Show summary »

Probable cationic amino acid transporter / SLC7A14 Show summary »

Target Id 895
Nomenclature Probable cationic amino acid transporter
Systematic nomenclature SLC7A14
Previous and unofficial names solute carrier family 7 (cationic amino acid transporter, y+ system), member 14 | solute carrier family 7 (orphan transporter), member 14 | solute carrier family 7, member 14 | solute carrier family 7 | solute carrier family 7 (cationic amino acid transporter
Genes SLC7A14 (Hs), Slc7a14 (Mm), Slc7a14 (Rn)
Ensembl ID ENSG00000013293 (Hs), ENSMUSG00000069072 (Mm), ENSRNOG00000028097 (Rn)
UniProtKB AC Q8TBB6 (Hs), Q8BXR1 (Mm)
Bioparadigms SLC Tables SLC7A14 (Hs)

LAT1 (L-type amino acid transporter 1 / SLC7A5) C Show summary » More detailed page go icon to follow link

LAT2 (L-type amino acid transporter 2 / SLC7A8) C Show summary »

y+LAT1 (y+L amino acid transporter 1 / SLC7A7) C Show summary »

y+LAT2 (y+L amino acid transporter 2 / SLC7A6) C Show summary »

b0,+AT (b0,+-type amino acid transporter 1 / SLC7A9) C Show summary »

Asc-1 (Asc-type amino acid transporter 1 / SLC7A10) C Show summary »

xCT (Cystine/glutamate transporter / SLC7A11) C Show summary »

AGT1 / SLC7A13 C Show summary »


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Further reading

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How to cite this family page

Database page citation (select format):

Concise Guide to PHARMACOLOGY citation:

Alexander SP, Kelly E, Mathie A, Peters JA, Veale EL et al. (2021) THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: Transporters. Br J Pharmacol. 178 Suppl 1:S412-S513.